Analysis of biopharma raw materials by electrophoresis microchips with contactless conductivity detection

Publication Type  Conference Paper
Year of Publication  2009
Authors  Vazquez, M.; Benito-Lopez, F.; Garcia-Cordero, J.; Ricco, A.; Diamond, D.
Conference Name  In: μTAS 2009 - 13th International Conference of Miniaturized Systems for Chemistry and Life Science, Micro Total Analysis Systems
Conference Date  1-5 Nov 2009
Conference Location  Jeju, Korea
ISBN Number  978-0-9798064-2-1
Key Words  RP1
Abstract  

Detailed information concerning the composition of the raw materials employed in the production of biologics is important for the efficient control and optimization of bioprocesses. We demonstrate the application of electrophoresis microchips with capacitively-coupled contactless conductivity detection (C4D) to the analysis of wa-ter-soluble vitamins and metal cations in raw material solutions that are subse-quently fed into bioreactors for the production of biologics.

URL  http://doras.dcu.ie/15002/